Landmark Research

The latest publications, abstracts & posters from Gameto

Publications

April 5, 2025

Translation of a human induced pluripotent stem cell-derived ovarian support cell product to a Phase 3 enabling clinical grade product for in vitro fertilization treatment

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January 23, 2025

Rapid human oogonia-like cell specification via transcription factor-directed differentiation

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October 25, 2024

Ovarian support cell in vitro maturation (OSC-IVM) results in healthy murine live births with no evidence of reprotoxicology in a multigenerational study

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August 7, 2024

Road to in vitro maturation (IVM), from basic science to an informed clinical practice

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July 8, 2024

Clinical procedures for in vitro maturation treatment

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May 30, 2024

Rescue in vitro maturation using ovarian support cells of human oocytes from conventional stimulation cycles yields oocytes with improved nuclear maturation and transcriptomic resemblance to in vivo matured oocytes

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May 2, 2024

Reproducible differentiation of pure ovarian support cells from clinical-grade hiPSCs as a novel infertility treatment

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March 28, 2024

Donor side effects experienced under minimal controlled ovarian stimulation (COS) with in vitro maturation (IVM) versus conventional COS for in vitro fertilization (IVF) treatment

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October 10, 2023

Human-induced pluripotent stem cell-derived ovarian support cell co-culture improves oocyte maturation in vitro after abbreviated gonadotropin stimulation

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April 10, 2023

Improved rescue of immature oocytes obtained from conventional gonadotropin stimulation cycles via human induced pluripotent stem cell-derived ovarian support cell co-culture

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February 21, 2023

Directed differentiation of human iPSCs to functional ovarian granulosa-like cells via transcription factor overexpression

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October 19, 2022

Towards reconstituting an ovary

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Abstracts & Posters

Characterization of the hormonal profiles during minimal stimulation protocols in normal responder women and the assessment of their pain level after oocyte retrieval

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Comparing Different Mini-Stimulations and the Retrieval Efficiency for Obtaining Immature Oocytes for In Vitro Maturation

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Human induced pluripotent stem cell-derived ovarian support cells improve the maturation rate of immature human oocytes in vitro

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Improvement in rescue in vitro maturation outcomes using co-culture with induced pluripotent stem cell-derived ovarian support cells

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In vitro matured oocytes co-cultured with human induced pluripotent stem cell-derived ovarian support cells display transcriptomic quality similar to in vivo matured oocytes

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Ovarian support cells derived from human induced pluripotent stem cells allow in vitro maturation of oocytes and embryo development in a mouse model

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An optimized approach to generate ovarian support cells from induced pluripotent stem cells: a platform to develop therapeutics for diseases of the female reproductive system

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Ovarian support cell lines differentiated from human induced pluripotent stem cells: multi-omics characterization of a platform to develop therapeutics for diseases of the female reproductive system

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Investigation of transcription factor function via in vitro recapitulation of human oogenesis

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